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Title	Research - Trudeau
Description	Matt Trudeau Lab - Research on hERG channels and cardiac
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trudeaulab.org Valuation

US$816,579

Last updated: 2023-05-18 18:17:02

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Trudeau Lab Search hERG ion channels Search Menu Research Lab Resources Covid-19 People Publications Recruiting Contact Patch Clamp Fluorometry (PCF) images of inside-out patches from Xenopus oocytes with hERG channels labelled with the L-ANAP fluorescent amino acid. Bright field image of the patch pipette (left) and fluorescence image of the membrane patch (right). Confocal images from Xenopus oocytes of hERG channels fused to the fluorescent protein Citrine (Left) and hERG-Citrine with free L-ANAP (Center) and hERG-Citrine labelled with L- ANAP using amber codon suppression (Right). The focus of the work in my lab is on voltage-activated potassium channels in the hERG-family of ion channels. hERG channels are known for their role in cardiac electrophysiology where they help to repolarize cardiac action potentials. Genetic mutations in hERG channels are linked to the long QT syndrome, a cardiac rhythm disorder that is characterized by a prolonged QT interval on an electrocardiogram

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